RDU to Chicago: the Research Triangle to the Loop, or the suburbs
Raleigh to Chicago is 630 miles, about an hour and three-quarters westbound in a light jet. Chicago is an hour behind, so an 8 am departure from Raleigh-Durham lands at Midway at about 8.45 am local time, early enough for a morning meeting downtown.
Where you land in Chicago depends on where the day is. Midway is twenty-five minutes from the Loop and River North. Several large life-science companies, AbbVie and Baxter among them, have their headquarters in the northern suburbs around North Chicago and Deerfield, twenty to thirty minutes from Chicago Executive. DuPage is the closer field for Oak Brook and Naperville. Either saves the drive across the city from Midway.
A day return is the usual pattern. The crew waits at the FBO while you are in meetings and you are home in Raleigh for a late dinner.